The occurrence of acute myeloid leukemia (AML) within six Little White Dress months from a diagnosis of breast cancer (BC) is rarely reported in the literature, and it is associated with a poor prognosis.We report herein the case of a 40-year-old woman referred to our centre affected by BC and simultaneous AML.The patient proved refractory to first line therapy and achieved complete remission (CR) with a clofarabine-based regimen followed by allogeneic stem cell transplantation (ASCT).Both during salvage chemotherapy and after ASCT, the patient presented severe infectious complications ( acute cholecistytis and Nocardia pneumonia, respectively) treated Champagne Stoppers with surgery, and currently she is alive in CR for both diseases after 29 months of follow-up.
The case highlights the importance of a diagnostic assessment of any unexplained cytopenia in association with solid neoplasia under treatment, underlining the feasibility and priority of a timely treatment of the haematological neoplasm in order to achieve long-term survival.